Insomnia Research Today is a free monthly online journal that collates and summarizes the latest research about Insomnia, including details on sleep disorders, treatment, medication. | ||||||
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Usefulness of mindfulness-based cognitive therapy for treating insomnia in patients with anxiety disorders: a pilot study.Yook K, Lee SH, Ryu M, Kim KH, Choi TK, Suh SY, Kim YW, Kim B, Kim MY, Kim MJ Department of Psychiatry-Bundang CHA Hospital, Pochon CHA University College of Medicine, Seongnam, Republic of Korea. The objective of this study was to examine the usefulness of a mindfulness-based cognitive therapy (MBCT) for treating insomnia symptoms in patients with anxiety disorder. Nineteen patients with anxiety disorder were assigned to an 8-week MBCT clinical trial. Participants showed significant improvement in Pittsburgh Sleep Quality Index (Z = -3.46, p = 0.00), Penn State Worry Questionnaire (Z = -3.83, p = 0.00), Ruminative Response Scale (Z = -3.83, p = 0.00), Hamilton Anxiety Rating Scale (Z = -3.73, p = 0.00), and Hamilton Depression Rating Scale scores (Z = -3.06, p = 0.00) at the end of the 8-week program as compared with baseline. Multiple regression analysis showed that baseline Penn State Worry Questionnaire scores were associated with baseline Pittsburgh Sleep Quality Index scores. These findings suggest that MBCT can be effective at relieving insomnia symptoms by reducing worry associated sleep disturbances in patients with anxiety disorder. However, well-designed, randomized, controlled trials are needed to confirm our findings. Published 16 June 2008 in J Nerv Ment Dis, 196(6): 501-3. Articles on Insomnia published 30 May 2008: Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time. Nat Rev Drug Discov, 7(6): 530-40. Sleep is essential for our physical and mental well being. However, when novel hypnotic drugs are developed, the focus tends to be on the marginal and statistically significant increase in minutes slept during the night instead of the effects on the quality of wakefulness. Recent research on the mechanisms underlying sleep and the control of the sleep-wake cycle has the potential to aid the development of novel hypnotic drugs; however, this potential has not yet been realized. Here, we review ... [Abstract] [Full-text] Articles on Insomnia published 19 March 2008: Potential pharmacokinetic basis for zolpidem dosing in children with sleep difficulties. Clin Pharmacol Ther, 83(4): 551-8. The pharmacokinetics of zolpidem was assessed in this open-label, dose-escalation study in children with insomnia. Twenty-one children, seven per age group (2-6, >6 to 12, >12 to 18 years), received a single dose of zolpidem at one of the three dose levels (0.125, 0.25, or 0.50 mg/kg (20 mg maximum dose)). Multiple pharmacokinetic measures were assessed at nine post-dose intervals and pharmacodynamics was assessed by polysomnography and actigraphy. Significant pharmacokinetic effects by ... [Abstract] [Full-text] Articles on Insomnia published 25 February 2008: Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study. Biol Psychiatry, 63(6): 629-32. BACKGROUND: Prazosin, a central nervous system (CNS) active alpha-1 adrenoreceptor antagonist, has reduced nightmares and sleep disturbance in placebo-controlled studies of combat-related posttraumatic stress disorder (PTSD). We evaluated objective sleep parameters and PTSD symptoms in a placebo-controlled prazosin trial for civilian trauma-related PTSD. METHODS: Thirteen outpatients with chronic civilian trauma PTSD, frequent nightmares, and sleep disturbance participated in a randomized ... [Abstract] [Full-text] Articles on Insomnia published 11 February 2008: Melatonin treatment in individuals with intellectual disability and chronic insomnia: a randomized placebo-controlled study. J Intellect Disabil Res, 52: 256-64. BACKGROUND: While several small-number or open-label studies suggest that melatonin improves sleep in individuals with intellectual disabilities (ID) with chronic sleep disturbance, a larger randomized control trial is necessary to validate these promising results. METHODS: The effectiveness of melatonin for the treatment of chronic sleep disturbance was assessed in a randomized double-blind placebo-controlled trial with 51 individuals with ID. All of these individuals presented with chronic ... [Abstract] [Full-text] Articles on Insomnia published 28 January 2008: Pharmacotherapy of insomnia. Expert Opin Pharmacother, 9(3): 351-62. Insomnia is the most common sleep disorder in the industrialized world. A variety of precipitating events have been identified, but when it becomes a persistent problem, maladaptive patterns become established, thereby, perpetuating the sleep disturbance. Individuals with insomnia have impaired next-day functioning, which impacts their quality of life and places them at increased risk of motor vehicle accidents. Insomnia is commonly associated with chronic medical conditions, as well as an ... [Abstract] [Full-text] Articles on Insomnia published 14 January 2008: Sleep health New South Wales: chronic sleep restriction and daytime sleepiness. Intern Med J, 38(1): 24-31. AIMS: The aim of this study was to provide the first population-based descriptions of typical sleep duration and the prevalence of chronic sleep restriction and chronic sleepiness in community-dwelling Australian adults. METHODS: Ten thousand subjects randomly selected from the New South Wales electoral roll, half aged 18-24 years and the other half aged 25-64 years were posted a questionnaire asking about sleep behaviour, sleepiness and sleep disorders. RESULTS: Responses were received from ... [Abstract] [Full-text] Articles on Insomnia published 30 November 2007: Efficacy of cognitive-behavioral therapy for insomnia associated with traumatic brain injury: a single-case experimental design. Arch Phys Med Rehabil, 88(12): 1581-92. OBJECTIVE: To test the efficacy of a cognitive-behavioral therapy (CBT) for insomnia in persons having sustained traumatic brain injury (TBI). DESIGN: Single-case design with multiple baselines across participants. SETTING: Outpatient rehabilitation center. PARTICIPANTS: Eleven subjects having sustained mild to severe TBI who developed insomnia after the injury. INTERVENTION: Eight-week CBT for insomnia including stimulus control, sleep restriction, cognitive restructuring, sleep hygiene ... [Abstract] [Full-text] Articles on Insomnia published 23 November 2007: Light therapy for insomnia in older adults. Clin Geriatr Med, 24(1): 139-49, viii. Exposure to bright light suppresses the production of melatonin and contributes to the regulation of the circadian rhythm. Because of environmental and medical conditions, older adults are less likely than younger adults to receive the prolonged, high intensity, daily bright light needed to promote a satisfactory sleep-wake cycle. The best available evidence for bright light therapy is in the management of seasonal affective disorder, which is relatively infrequent in the elderly population. ... [Abstract] [Full-text] © 2004-2008 Insomnia Research Today. All Rights Reserved. |
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